LISINOPRIL-INDUCED HYPERPIGMENTATION

Purpose: For patients with hypertension, cardiovascular disease, and diabetes, lisinopril is a commonly prescribed angiotensin-converting enzyme (ACE) inhibitor. While known to have adverse cutaneous reactions such as pruritus and angioedema, we present a case of hyperpigmenting, desquamating rash in a 54 year-old African American woman. Methods: The information was gathered from patient chart review. Results: Upon discontinuation of lisinopril, the subject's rash resolved. Conclusions: For patients on ACE inhibitors, development of a hyperpigmenting, desquamating rash should considered an adverse cutaneous reaction.