University Publications
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The Effects of Cognitive Impairment on Hospitalizations in Heart Failure Patients
(2018-05)Background: Heart failure (HF) is a major health problem in the United States (US) linked to poor survival rates, high rehospitalization rates and high healthcare cost. HF is positively associated with aging and its impact ... -
The Association Between Sleep Traits and the Risk of Lung Cancer: UK Biobank Cohort
(2022-05)Background: Lung cancer has the highest incidence of any cancer and is the leading cause of cancer-related death worldwide. As smoking rates have declined over the last few decades, the proportion of individuals diagnosed ... -
Three-dimensional variation in maxillary sinus anatomy: Implications for health disparities in sinonasal disease
(2022-05)Sinusitis affects approximately 30 million Americans annually and is associated with negative quality of life, overuse of antibiotics, and high healthcare costs. As the maxillary sinus (MS) is the sinus most commonly ... -
The Impact of Travel Stressors on the Pathogenesis of Autoimmunity in Female Lupus Mice
(2022-05)Preliminary studies found that an established model of systemic lupus erythematosus, the female NZBWF1 mouse, developed heightened disease severity later in life when shipped to UNTHSC during summer due to travel stressors. ... -
Hemodynamic Oscillations: Physiological Consequences and Therapeutic Potential
(2022-05)Hemorrhage, or massive blood loss, continues to be a leading cause of preventable death. Therapeutic approaches that protect vital organ function are needed to improve outcomes from hemorrhage. In this dissertation, I ... -
Effects of Sex, Life Stage, and Specific Blood Meals on Microbiome of Starved Ornithodoros turicata
(2022-05)Ticks carry and transmit more disease agents than any other arthropod vector. The composition of the microbiome within ticks may influence this ability, but many factors that influence their microbial composition remain ... -
Comparing Short-Term Radiographic Outcomes of Cementless Primary Reverse Total Shoulder Arthroplasty Implantation With and Without Augmentation by Humeral Matchstick Autograft: A Retrospective Cohort Study
(2021-12)Reverse Total Shoulder Arthroplasty (RTSA) is an arthroplasty procedure that is increasing in incidence in the United States (26). As the incidence of the procedure increases, the gross number of RTSA complications is also ... -
Roadblocks in Clinical Research: An Analysis of Common Barriers to the Clinical Research Process
(2022-12)Deficiencies in the clinical research process can lead to delays, loss of funding, outdated conclusions, and a lack in participation for both volunteers and scientists or clinicians. This project aimed to identify the ... -
The Role of LLT1 (CLEC2D, OCIL) in Ewing Sarcoma
(2021-12)Ewing Sarcoma (EWS) is a pediatric bone cancer that is characterized by a chromosomal translocation giving rise to a neomorphic gene fusion. Although treatment of EWS has a 5-year incident free survival rate of 66%, treatment ... -
Oral and gut microbiome in chronic sleep restriction mice models
(2020-12)Reduced sleep quality is a common problem in the US, linked to increased risk for several disease conditions. Current evidence indicates an association between the gut microbiome and sleep modulation. With the ease of ... -
The role of built environment and private rooms for reducing hospital acquired infections
(2019-08)Increased use of private patient rooms may be an important adjunct to traditional process-based interventions to prevent hospital-acquired infections (HAIs) in inpatient settings. We examined whether private room assignment ... -
Aging impairs regulatory T cells to affect the mouse model of late-onset multiple sclerosis
(2022-08)Although multiple sclerosis (MS) primarily onsets in young adults, it can also develop in the elderly, which is termed late-onset (aged) MS. CD4+ Foxp3 + regulatory T (Treg) cells play an ameliorative role in severity of ... -
Do brief motivational interventions increase motivation for change in drinking among college students? A meta-analysis of individual participant data
(2022-08)Brief Motivational Interventions (BMIs) have been identified as one of the most effective individually focused alcohol intervention strategies for college students in the United States. Despite the central role of motivation ... -
Examining the skin and workplace microbiome following the return to the University of North Texas Health Science Center after self-isolation
(2021-08)The human skin microbiome contains trillions of microbiomes that colonize the human body. It is unknown how social distancing and an increase in handwashing due to the COVID-19 pandemic affect the bacterial communities ... -
The impact of early life stressors on the progression of SLE
(2021-08)Our preliminary studies show that an established model of systemic lupus erythematosus (SLE), the female NZBWF1 mouse, had worsened indices of disease later in life when the mice were shipped to our institution at an early ... -
The role of lipid rafts in androgen's neurotoxic effects
(2021-08)Sex differences have been observed in multiple oxidative stress (OS) associated neurodegenerative diseases. Androgens, the major male sex hormone, through a membrane androgen receptor (mAR) localized to lipid rafts in the ... -
Interplay between metabolic and myogenic mechanisms in coronary pressure-flow autoregulation
(2022-05)The local metabolic hypothesis proposes that myocardial oxygen tension, indexed by coronary venous PO2 (CvPO2), determines the degree of coronary pressure-flow autoregulation. Conversely, the myogenic hypothesis proposes ...
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