Novel Methods for Processing Biological Samples Stored Onto FTA® Paper

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dc.contributor.advisorArthur J. Eisenberg
dc.contributor.committeeMemberRafael Alvarez
dc.contributor.committeeMemberJohn Planz
dc.creatorAranda, Xavier G.
dc.date.accessioned2019-08-22T21:07:42Z
dc.date.available2019-08-22T21:07:42Z
dc.date.issued2003-05-01
dc.date.submitted2013-11-18T12:54:15-08:00
dc.description.abstractAranda, Xavier G., Novel Methods for Processing Samples Stored Onto FTA® Paper. Masters of Science (Biomedical Sciences), May, 2003, 76 pp., 10 tables, 17 illustrations, bibliography, 30 titles. The goal was to develop methodologies to facilitate the processing of samples stored on FTA® paper for paternity and forensic testing. The research was divided into three major areas. The first was an evaluation of the stability of the different FTA® matrices, and the development of a process which would maximize the amount of genetic information that could be obtained from a single 1.2 mm FTA® punch. The second was the development of a process for the efficient elution of the DNA trapped within the FTA® matrix. This would facilitate the use of FTA® technology with high throughput robotic processing systems. The third was the development of methodologies which would allow the integration of FTA® technology with a non-invasive buccal swab collection process. The methods developed from these studies are now used in the DNA Identity Laboratory at UNTHSC and many other laboratories throughout the world for routine casework analysis.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/20.500.12503/29091
dc.language.isoen
dc.provenance.legacyDownloads0
dc.subjectEquipment and Supplies
dc.subjectGenetics
dc.subjectGenetics and Genomics
dc.subjectInvestigative Techniques
dc.subjectLife Sciences
dc.subjectMedical Genetics
dc.subjectMedicine and Health Sciences
dc.subjectOther Genetics and Genomics
dc.subjectNovel methods
dc.subjectprocessing samples
dc.subjectFTA® paper
dc.subjectmatrices
dc.subjectgenetic information
dc.subjectbuccal swab collection process
dc.subjectDNA Identity Laboratory
dc.subjectUNTHSC
dc.subjectroutine casework analysis
dc.subjecthigh throughput robotic processing systems
dc.subjectDNA
dc.titleNovel Methods for Processing Biological Samples Stored Onto FTA® Paper
dc.typeThesis
dc.type.materialtext
thesis.degree.departmentGraduate School of Biomedical Sciences
thesis.degree.disciplineBiomedical Sciences
thesis.degree.grantorUniversity of North Texas Health Science Center at Fort Worth
thesis.degree.nameMaster of Science

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