Age-related Impairment of Vascular Structure and Functions

Date
2017-10-01
Authors
Xu, Xianglai
Wang, Brian
Ren, Changhong
Hu, Jiangnan
Greenberg, David A.
Chen, Tianxiang
Xie, Liping
Jin, Kunlin
ORCID
0000-0002-1336-348X (Jin, Kunlin)
Journal Title
Journal ISSN
Volume Title
Publisher
JKL International
Abstract

Among age-related diseases, cardiovascular and cerebrovascular diseases are major causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age is an independent and essential risk factor. The present work will review morphological alterations of aging vessels in-depth, which includes the discussion of age-related microvessel loss and changes to vasculature involving the capillary basement membrane, intima, media, and adventitia as well as the accompanying vascular dysfunctions arising from these alterations.

Description
Citation
Xu, X., Wang, B., Ren, C., Hu, J., Greenberg, D. A., Chen, T., Xie, L., & Jin, K. (2017). Age-related Impairment of Vascular Structure and Functions. Aging and disease, 8(5), 590-610. https://doi.org/10.14336/AD.2017.0430