Age-related Impairment of Vascular Structure and Functions

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dc.creatorXu, Xianglai
dc.creatorWang, Brian
dc.creatorRen, Changhong
dc.creatorHu, Jiangnan
dc.creatorGreenberg, David A.
dc.creatorChen, Tianxiang
dc.creatorXie, Liping
dc.creatorJin, Kunlin
dc.creator.orcid0000-0002-1336-348X (Jin, Kunlin)
dc.date.accessioned2022-09-09T14:08:38Z
dc.date.available2022-09-09T14:08:38Z
dc.date.issued2017-10-01
dc.description.abstractAmong age-related diseases, cardiovascular and cerebrovascular diseases are major causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age is an independent and essential risk factor. The present work will review morphological alterations of aging vessels in-depth, which includes the discussion of age-related microvessel loss and changes to vasculature involving the capillary basement membrane, intima, media, and adventitia as well as the accompanying vascular dysfunctions arising from these alterations.
dc.description.sponsorshipThe work of the first author, XX, was supported by China Scholarship Council (No. 201406320118). This work was also supported by the American Heart Association Predoctoral Fellowship (15PRE25700416) (to BW), Sigma Xi Grants-in-Aid of Research (G201503151162287) (to BW), National Natural Science Foundation of China (81301996) (to TC), Ph.D. Programs Foundation of Ministry of Education of China (20130101120017) (to TC).
dc.identifier.citationXu, X., Wang, B., Ren, C., Hu, J., Greenberg, D. A., Chen, T., Xie, L., & Jin, K. (2017). Age-related Impairment of Vascular Structure and Functions. Aging and disease, 8(5), 590-610. https://doi.org/10.14336/AD.2017.0430
dc.identifier.issn2152-5250
dc.identifier.issue5
dc.identifier.urihttps://hdl.handle.net/20.500.12503/31685
dc.identifier.volume8
dc.publisherJKL International
dc.relation.urihttps://doi.org/10.14336/AD.2017.0430
dc.rights.holder© 2017 Xu X, et al.
dc.rights.licenseAttribution 4.0 International (CC BY 4.0)
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceAging and Disease
dc.subjectarterial stiffness
dc.subjectendothelial dysfunction
dc.subjectvascular aging
dc.subjectvascular remodeling
dc.titleAge-related Impairment of Vascular Structure and Functions
dc.typeArticle
dc.type.materialtext

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