Adipose Stem Cells in Regenerative Medicine: Looking Forward

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dc.creatorAl-Ghadban, Sara
dc.creatorArtiles, Maria
dc.creatorBunnell, Bruce A.
dc.creator.orcid0000-0001-6196-3722 (Bunnell, Bruce A.)
dc.date.accessioned2022-08-25T15:39:44Z
dc.date.available2022-08-25T15:39:44Z
dc.date.issued2022-01-13
dc.description.abstractOver the last decade, stem cell-based regenerative medicine has progressed to clinical testing and therapeutic applications. The applications range from infusions of autologous and allogeneic stem cells to stem cell-derived products. Adult stem cells from adipose tissue (ASCs) show significant promise in treating autoimmune and neurodegenerative diseases, vascular and metabolic diseases, bone and cartilage regeneration and wound defects. The regenerative capabilities of ASCs in vivo are primarily orchestrated by their secretome of paracrine factors and cell-matrix interactions. More recent developments are focused on creating more complex structures such as 3D organoids, tissue elements and eventually fully functional tissues and organs to replace or repair diseased or damaged tissues. The current and future applications for ASCs in regenerative medicine are discussed here.
dc.description.sponsorshipThis work was supported by NIH Grants UG3TR002136 and UG3TR003090.
dc.identifier.citationAl-Ghadban, S., Artiles, M., & Bunnell, B. A. (2022). Adipose Stem Cells in Regenerative Medicine: Looking Forward. Frontiers in bioengineering and biotechnology, 9, 837464. https://doi.org/10.3389/fbioe.2021.837464
dc.identifier.issn2296-4185
dc.identifier.urihttps://hdl.handle.net/20.500.12503/31641
dc.identifier.volume9
dc.publisherFrontiers Media S.A.
dc.relation.urihttps://doi.org/10.3389/fbioe.2021.837464
dc.rights.holderCopyright © 2022 Al-Ghadban, Artiles and Bunnell.
dc.rights.licenseAttribution 4.0 International (CC BY 4.0)
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceFrontiers in Bioengineering and Biotechnology
dc.subjectadipose-derived stem cells (ASCs)
dc.subjectmicrofluidic systems
dc.subjectregenerative medicine
dc.subjectscaffolds
dc.subjecttissue engineering
dc.titleAdipose Stem Cells in Regenerative Medicine: Looking Forward
dc.typeArticle
dc.type.materialtext

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